Data CitationsHerdy JR, Schafer S, Kim Y, Ansari Z, Zangwill D, Ku M, Paquola ACM, Lee H, Mertens J, Gage FH. and NC+ZPAK media. Annotare. E-MTAB-7250Miller JA, Guillozet-Bongaarts A, Gibbons LE, Postupna N, Renz A, Beller AE, Sunkin SM, Ng L, Rose SE, Smith KA, Szafer A, Barber C, Bertagnolli D, Bickley K, Brouner K, Caldejon S, Chapin M, BAY1238097 Chua ML, Coleman NM, Cudaback E, Cuhaciyan C, Dalley RA, Dee N, Desta T, Dolbeare TA, Dotson NI, Fisher M, Gaudreault N, Gee G, Gilbert TL, Goldy J, Griffin F, Habel C, Haradon Z, Hejazinia N, Hellstern LL, Horvath S, Howard K, Howard R, Johal J, Jorstad NL, Josephsen SR, Kuan CL, Lai F, Lee E, Lee F, Lemon T, Li X, Marshall DA, Melchor J, Mukherjee Rabbit Polyclonal to STEA2 S, Nyhus J, Pendergraft J, Potekhina L, Rha EY, Rice S, Rosen D, Sapru A, Schantz A, Shen E, Sherfield E, Shi S, Sodt AJ, Thatra N, Tieu M, Wilson AM, Montine TJ, Larson EB, Bernard A, Crane PK. 2017. gene_expression_matrix_2016_03_03. Aging, Dementia and Traumatic Brain Injury Study. 502999992Miller JA, Ding SL, Sunkin SM, Smith KA, Ng L, Szafer A, Ebbert A, Riley ZL, Royall JJ, Aiona K, Arnold JM, Bennet C, Bertagnolli D, Brouner K, Butler S, Caldejon S, Carey A, Cuhaciyan C, Dalley RA, Dee N, Dolbeare TA, Facer BA, Feng D, Fliss TP, Gee G, Goldy J, Gourley L, Gregor BW, Gu G, Howard RE, Jochim JM, Kuan CL, Lau C, Lee CK, Lee F, Lemon TA, Lesnar P, McMurray B, Mastan N, Mosqueda N, Naluai-Cecchini T, Ngo NK, Nyhus J, Oldre A, Olson E, Parente J, Parker PD, Parry SE, Stevens A, Pletikos M, Reding M, Roll K, Sandman D, Sarreal M, Shapouri S, Shapovalova NV, Shen EH, Sjoquist N, Slaughterbeck CR, Smith M, Sodt AJ, Williams D, Z?llei L, Fischl B, Gerstein MB, Geschwind DH, Glass IA, Hawrylycz MJ, Hevner RF, Huang H, Jones AR, Knowles JA, Levitt P, Phillips JW, Sestan N, Wohnoutka P, Dang C. 2014. RNA-Seq Gencode v10 summarized to genes. BrainSpan Atlas of the Developing Human Brain. 267666525Supplementary MaterialsFigure 1source data 1: Human fibroblasts used in this study. elife-41356-fig1-data1.pdf (19K) DOI:?10.7554/eLife.41356.004 Figure 2source data 1: Ingenuity pathway analysis of direct fibroblast to neuron conversion. elife-41356-fig2-data1.xls (223K) DOI:?10.7554/eLife.41356.010 Figure 2source data 2: Expanded small molecule information. elife-41356-fig2-data2.pdf (22K) DOI:?10.7554/eLife.41356.007 Figure 3source data 1: Significantly differentially expressed genes between NC and NC+ZPAK. elife-41356-fig3-data1.txt (115K) DOI:?10.7554/eLife.41356.018 Transparent reporting form. elife-41356-transrepform.docx (245K) DOI:?10.7554/eLife.41356.023 Data Availability StatementSequencing data have BAY1238097 been deposited in Annotare under accession codes E-MTAB-7250, E-MTAB-7226, and E-MTAB-7259. The following datasets had been generated: Herdy JR, Schafer S, Kim Y, Ansari Z, Zangwill D, Ku M, Paquola ACM, Lee H, Mertens J, Gage FH. 2019. Methylation selection of youthful, mid age group, and outdated induced neurons cultured in NC+ZPAK, aswell simply because unconverted young and old fibroblast. Annotare. E-MTAB-7226 Herdy JR, Schafer S, Kim Y, Ansari Z, Zangwill D, Ku M, Paquola ACM, Lee H, Mertens J, Gage FH. 2019. Timeline RNAseq of fibroblast to neuron path transformation. Annotare. E-MTAB-7259 Herdy JR, Schafer S, Kim Y, Ansari Z, Zangwill D, Ku M, Paquola ACM, Lee H, Mertens J, Gage FH. 2019. RNA-seq timeline of fibroblast to neuron transformation using traditional NC mass media and NC+ZPAK mass media. Annotare. E-MTAB-7250 The next previously released datasets were utilized: Miller JA, Guillozet-Bongaarts A, Gibbons LE, Postupna N, Renz A, Beller AE, Sunkin SM, Ng L, Rose SE, Smith KA, Szafer A, Barber C, Bertagnolli D, Bickley K, Brouner K, Caldejon S, Chapin M, Chua ML, Coleman NM, Cudaback E, Cuhaciyan C, Dalley RA, Dee N, Desta T, Dolbeare TA, Dotson NI, Fisher M, Gaudreault N, Gee G, Gilbert TL, Goldy J, Griffin F, Habel C, Haradon Z, Hejazinia N, Hellstern LL, Horvath S, Howard K, Howard R, Johal J, Jorstad NL, Josephsen SR, Kuan CL, Lai F, Lee E, Lee F, Lemon T, Li X, Marshall DA, Melchor J, Mukherjee S, Nyhus J, Pendergraft J, Potekhina L, Rha EY, Grain S, Rosen D, Sapru A, Schantz A, Shen E, Sherfield E, Shi S, Sodt AJ, Thatra N, Tieu M, Wilson AM, Montine TJ, Larson EB, Bernard A, Crane PK. 2017. gene_appearance_matrix_2016_03_03. Maturing, Dementia and Traumatic Human brain Injury Research. 502999992 Miller JA, Ding SL, Sunkin SM, Smith KA, Ng L, Szafer A, Ebbert A, Riley ZL, Royall JJ, Aiona K, Arnold JM, Bennet C, Bertagnolli D, Brouner K, Butler S, Caldejon S, Carey A, Cuhaciyan C, Dalley RA, Dee N, Dolbeare TA, Facer BA, Feng D, Fliss TP, Gee G, Goldy J, Gourley L, Gregor BW, Gu G, Howard RE, Jochim JM, Kuan CL, Lau C, Lee CK, Lee F, Lemon TA, Lesnar P, BAY1238097 McMurray B, Mastan N, Mosqueda.